Our new article has been accepted in Scientific Reports: Löchel HF, Heider D: Comparative analyses of error handling strategies for next-generation sequencing in precision medicine. Scientific Reports 2020, 10:5750. (Link) Abstract Next-generation sequencing (NGS) offers the opportunity to sequence millions and billions of DNA sequences in a short period, leading to novel applications in personalized…
Our new article has been accepted in Bioinformatics: Schwarz M, Welzel M, Kabdullayeva T, Becker A, Freisleben B, Heider D: MESA: automated assessment of synthetic DNA fragments and simulation of DNA synthesis, storage, sequencing, and PCR errors. Bioinformatics 2020, in press. (Link) Abstract Summary The development of de novo DNA synthesis, PCR, DNA sequencing, and…
Within the interdisciplinary Medical Informatics research division, the Faculty of Mathematics and Computer Science – Bioinformatics Group, Prof. Dr. Dominik Heider, offers one position as Research Assistant (Ph.D. student) The open Ph.D. position is an integral part of the collaboration with the Humangenetics department of the University Hospital Marburg and the Center for Addiction and…
In order to optimally benefit from the synergy effects of Bio- and Biomedical Informatics at the University of Marburg, close networking between corresponding Groups and faculties such as Mathematics & Computer Science, Biology, Medicine and Pharmacy are essential. The Symposium will offer an appropriate platform to support such interdisciplinary communication and interaction, to foster collaborations…
Our new article has been accepted in Scientific Data: Hackl T., Martin R., Barenhoff K., Duponchel S., Heider D., Fischer M.G.: Four high-quality draft genome assemblies of the marine heterotrophic nanoflagellate Cafeteria roenbergensis. Scientific Data 2020, 7:29 (Link) Abstract The heterotrophic stramenopile Cafeteria roenbergensis is a globally distributed marine bacterivorous protist. This unicellular flagellate is…
Within the interdisciplinary research project FeatureCloud (https://featurecloud.eu/), the Faculty of Mathematics and Computer Science – Bioinformatics Group, Prof. Dr. Dominik Heider, offers a position as Research Assistant (Ph.D. student) The open Ph.D. position is an integral part of the European FeatureCloud project. The primary objective of FeatureCloud is a novel kind of medical data mining…
Our new article has been accepted in Clinical Gastroenterology and Hepatology: Best J, Bechmann LP, Sowa LP, Sydor S, Dechêne A, Pflanz K, Bedreli S, Schotten C, Geier A, Berg T, Fischer J, Vogel A, Bantel H, Weinmann A, Schattenberg JM, Huber Y, Wege H, von Felden J, Schulze K, Bettinger D, Thimme R, Sinner…
Our project Deep-iAMR: Identification of new antimicrobial resistance targets by high-throughput deep learning has just been granted by the BMBF (031L0209B). The partner in the project is the University of Gießen. Abstract According to the World Health Organization (WHO), antibiotic resistance is one of the biggest threats to global health, food security, and development today.…
Our project Systems Biology guided Machine Learning in Pharmacogenomics for Predicting Antidepressant Non-Remission In Late-Life Depression has just been granted by the DAAD. The partner in the project is Prof. Daniel Mueller from the University of Toronto. Abstract Late-life depression (LLD), which is the occurrence of major depressive disorder (MDD) in older adults (age ≥60 years),…
Luis Ceze from the University of Washington gave a talk on DNA data storage systems within our MOSLA project meeting at the Department of Mathematics and Computer Science at the University of Marburg.
