New publication!

Our new article has been accepted in Cell iScience: Martin R, Löchel HF, Welzel M, Hattab G, Hauschild AC, Heider D: CORDITE: the curated CORona Drug InTERactions database for SARS-CoV-2. Cell iScience 2020 (Link) Abstract The biology Since the outbreak in 2019, researchers are trying to find effective drugs against the SARS-CoV-2 virus based on…

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New publication!

Our new article has been accepted in Scientific Reports: Sperlea T, Muth L, Martin R, Weigel C, Waldminghaus T, Heider D: gammaBOriS: Identification and Taxonomic Classification of Origins of Replication in Gammaproteobacteria using Motif- based Machine Learning. Scientific Reports 2020, 10:6727. (Link) Abstract The biology of bacterial cells is, in general, based on information encoded…

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CORDITE

We created CORDITE (CORona Drug InTEractions database) an open database that collects and aggregates all available data from publications and preprints for SARS-CoV-2. Its focus is set on drug interactions. corona.mathematik.uni-marburg.decordite.mathematik.uni-marburg.de Please contribute to the open, curated database! UPDATES April 24, 2020CORDITE in numbers: 547 interactions (+17%), 423 drugs (+19%), 226 papers (+12%). NEW: GUI…

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New publication!

Our new article has been accepted in Scientific Reports: Löchel HF, Heider D: Comparative analyses of error handling strategies for next-generation sequencing in precision medicine. Scientific Reports 2020, 10:5750. (Link) Abstract Next-generation sequencing (NGS) offers the opportunity to sequence millions and billions of DNA sequences in a short period, leading to novel applications in personalized…

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New publication!

Our new article has been accepted in Bioinformatics: Schwarz M, Welzel M, Kabdullayeva T, Becker A, Freisleben B, Heider D: MESA: automated assessment of synthetic DNA fragments and simulation of DNA synthesis, storage, sequencing, and PCR errors. Bioinformatics 2020, in press. (Link)   Abstract Summary The development of de novo DNA synthesis, PCR, DNA sequencing, and…

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PhD student (Medical Informatics – Data Science)

Within the interdisciplinary Medical Informatics research division, the Faculty of Mathematics and Computer Science – Bioinformatics Group, Prof. Dr. Dominik Heider, offers one position as Research Assistant (Ph.D. student) The open Ph.D. position is an integral part of the collaboration with the Humangenetics department of the University Hospital Marburg and the Center for Addiction and…

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Symposium on Interdisciplinary Bioinformatics and Biomedical Data Science

In order to optimally benefit from the synergy effects of Bio- and Biomedical Informatics at the University of Marburg, close networking between corresponding Groups and faculties such as Mathematics & Computer Science, Biology, Medicine and Pharmacy are essential. The Symposium will offer an appropriate platform to support such interdisciplinary communication and interaction, to foster collaborations…

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New publication!

Our new article has been accepted in Scientific Data: Hackl T., Martin R., Barenhoff K., Duponchel S., Heider D., Fischer M.G.: Four high-quality draft genome assemblies of the marine heterotrophic nanoflagellate Cafeteria roenbergensis. Scientific Data 2020, 7:29 (Link)   Abstract The heterotrophic stramenopile Cafeteria roenbergensis is a globally distributed marine bacterivorous protist. This unicellular flagellate is…

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PhD student (Medical Informatics)

Within the interdisciplinary research project FeatureCloud (https://featurecloud.eu/), the Faculty of Mathematics and Computer Science – Bioinformatics Group, Prof. Dr. Dominik Heider, offers a position as Research Assistant (Ph.D. student) The open Ph.D. position is an integral part of the European FeatureCloud project. The primary objective of FeatureCloud is a novel kind of medical data mining…

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New publication!

Our new article has been accepted in Clinical Gastroenterology and Hepatology: Best J, Bechmann LP, Sowa LP, Sydor S, Dechêne A, Pflanz K, Bedreli S, Schotten C, Geier A, Berg T, Fischer J, Vogel A, Bantel H, Weinmann A, Schattenberg JM, Huber Y, Wege H, von Felden J, Schulze K, Bettinger D, Thimme R, Sinner…

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