Our new article has been accepted in EBioMedicine: Hess T, Maj C, Gehlen J, Borisov O, Haas SL, Gockel I, et al.: Dissecting the genetic heterogeneity of gastric cancer. EBioMedicine 2023, 92:104616. (Link) Summary Background Gastric cancer (GC) is clinically heterogenous according to location (cardia/non-cardia) and histopathology (diffuse/intestinal). We aimed to characterize the genetic risk…
Our new article has been accepted in Frontiers in Medicine: Jung AL, Han M, Griss K, Bertrams W, Nell C, Greulich T, Klemmer A, Pott H, Heider D, Vogelmeier CF, Hippenstiel S, Suttorp NW, Schmeck BT: Novel protein biomarkers for pneumonia and acute exacerbations in COPD: a pilot study. Frontiers in Medicine 2023, 10:1180746. (Link)…
Our new article has been accepted in Frontiers in Genetics: Klau JH, Maj C, Klinkhammer H, Krawitz PM, Mayer A, Hilmmer AM, Schumacher J, Heider D: AI-based multi-PRS models outperform classical single-PRS models. Frontiers in Genetics 2023, 14:1217860. (Link) Abstract Polygenic risk scores (PRS) calculate the risk for a specific disease based on the weighted…
Our new article has been accepted in CSBJ: Müller P, Velazquez Camacho O, Yazbeck AM, Wölwer C, Zhai W, Schumacher J, Heider D, Buettner R, Quaas A, Hillmer AM: Why loss of Y? A pan-cancer genome analysis of tumors with loss of Y chromosome. Computational and Structural Biotechnology Journal 2023, 21:1573-1583. (Link) Abstract Loss of…
Our new article has been accepted in Bioinformatics: Martin R, Nguyen MK, Lowack N, Heider D: ODNA: Identification of Organellar DNA by Machine Learning. Bioinformatics 2023, in press. (Link) Abstract MotivationIdentifying organellar DNA, such as mitochondrial or plastid sequences, inside a whole genome assembly, remains challenging and requires biological background knowledge. To address this, we…
Our new article has been accepted in Infection: Jung AL, Møller Jørgensen M, Bæk R, Artho M, Griss K, Han M, Bertrams W, Greulich T, Koczulla R, Hippenstiel S, Heider D, Suttorp N, Schmeck B: Surface proteome of plasma extracellular vesicles as mechanistic and clinical biomarkers for malaria. Infection 2023, in press. (Link) Abstract Purpose…
Our new article has been accepted in Computational and Structural Biotechnology Journal: Ezekannagha C, Welzel M, Heider D, Hattab G: DNAsmart: Multiple Attribute Ranking Tool for DNA Data Storage Systems Author links open overlay panel. Computational and Structural Biotechnology Journal 2023, 1448-1460 (Link) Abstract In an ever-growing need for data storage capacity, the Deoxyribonucleic Acid…
Our new article has been accepted in Nature Communications: Welzel M, Schwarz PM, Löchel HF, Kabdullayeva T, Clemens S, Becker A, Freisleben B, Heider D. DNA-Aeon provides flexible arithmetic coding for constraint adherence and error correction in DNA storage. Nature Communications 2023, 14:628. (Link) Abstract The extensive information capacity of DNA, coupled with decreasing costs…
Our new article has been accepted in Lancet Digital Health: Näher AF, Vorisek CN, Klopfenstein SAI, Lehne M, Thun S, Alsalamah S, Pujari S, Heider D, Ahrens W, Pigeot I, Marckmann G, Jenny MA, Renard BY, von Kleist M, Wieler LH, Balzer F, Grabenhenrich L. Secondary data for global health digitalisation. Lancet Digital Health 2023,…
Our new article has been accepted in Cancer Research: Namba S, Saito Y, Kogure Y, Masuda T, Bondy ML, Gharahkhani P, Gockel I, Heider D, Hillmer A, Jankowski J, MacGregor S, Maj C, Melin B, Ostrom QT, Palles C, Schumacher J, Tomlinson I, Whiteman DC, Okada Y, Kataoka K: Common Germline Risk Variants Impact Somatic…
