Our new article has been accepted in Scientific Reports: Sperlea T, Muth L, Martin R, Weigel C, Waldminghaus T, Heider D: gammaBOriS: Identification and Taxonomic Classification of Origins of Replication in Gammaproteobacteria using Motif- based Machine Learning. Scientific Reports 2020, 10:6727. (Link) Abstract The biology of bacterial cells is, in general, based on information encoded…
We created CORDITE (CORona Drug InTEractions database) an open database that collects and aggregates all available data from publications and preprints for SARS-CoV-2. Its focus is set on drug interactions. corona.mathematik.uni-marburg.decordite.mathematik.uni-marburg.de Please contribute to the open, curated database! UPDATES April 24, 2020CORDITE in numbers: 547 interactions (+17%), 423 drugs (+19%), 226 papers (+12%). NEW: GUI…
Our new article has been accepted in Scientific Reports: Löchel HF, Heider D: Comparative analyses of error handling strategies for next-generation sequencing in precision medicine. Scientific Reports 2020, 10:5750. (Link) Abstract Next-generation sequencing (NGS) offers the opportunity to sequence millions and billions of DNA sequences in a short period, leading to novel applications in personalized…
Our new article has been accepted in Bioinformatics: Schwarz M, Welzel M, Kabdullayeva T, Becker A, Freisleben B, Heider D: MESA: automated assessment of synthetic DNA fragments and simulation of DNA synthesis, storage, sequencing, and PCR errors. Bioinformatics 2020, in press. (Link) Abstract Summary The development of de novo DNA synthesis, PCR, DNA sequencing, and…
Our new article has been accepted in Scientific Data: Hackl T., Martin R., Barenhoff K., Duponchel S., Heider D., Fischer M.G.: Four high-quality draft genome assemblies of the marine heterotrophic nanoflagellate Cafeteria roenbergensis. Scientific Data 2020, 7:29 (Link) Abstract The heterotrophic stramenopile Cafeteria roenbergensis is a globally distributed marine bacterivorous protist. This unicellular flagellate is…
Our new article has been accepted in Clinical Gastroenterology and Hepatology: Best J, Bechmann LP, Sowa LP, Sydor S, Dechêne A, Pflanz K, Bedreli S, Schotten C, Geier A, Berg T, Fischer J, Vogel A, Bantel H, Weinmann A, Schattenberg JM, Huber Y, Wege H, von Felden J, Schulze K, Bettinger D, Thimme R, Sinner…
Our new article has been accepted in Frontiers in Genetics: Martin R, Heider D: ContraDRG: Automatic partial charge prediction by Machine Learning, Frontiers in Genetics 2019, in press. (Link) Abstract In recent years, machine learning techniques have been widely used in biomedical research to predict unseen data based on models trained on experimentally derived data.…
Our new article has been accepted in Artificial Intelligence in Medicine: Spänig S, Emberger-Klein A, Sowa JP, Canbay A, Menrad K, Heider D: The Virtual Doctor: An Interactive Clinical-Decision-Support System based on Deep Learning for Non-Invasive Prediction of Diabetes, Artificial Intelligence in Medicine 2019, in press. (Link) Abstract Artificial intelligence (AI) will pave the way…
Our new article has been accepted in Liver Cancer: Schotten C, Bechmann LP, Manka P, Theysohn J, Dechêne A, El Fouly A, Barbato F, Neumann U, Radünz S, Sydor S, Heider D, Venerito M, Canbay A, Gerken G, Herrmann K, Wedemeyer H, Best J: NAFLD-associated comorbidities in advanced stage HCC do not alter the safety…
Our new article has been accepted in Bioinformatics: Löchel HF, Eger D, Sperlea T, Heider D: Deep Learning on Chaos Game Representation for Proteins. Bioinformatics 2019, in press. Abstract Motivation: Classification of protein sequences is one big task in bioinformatics and has many applications. Different machine learning methods exist and are applied on these problems,…
