Theodor Sperlea

since April 2017
PhD student in the Heider Lab, Department of Mathematics & Computer Science, University of Marburg, Germany
Focus: Machine Learning, Bioinformatics, Microbial Ecology, Genomics

2011 – 2017
Studies in Biology (Bachelor of Science) and Molecular & Cellular Biology (Master of Science) at Philipps-Universität Marburg, Germany
Title of Bachelor Thesis: The Role of the DnaA-Box in the Origin of the Secondary Chromosome in Vibrio cholerae
Title of Master Thesis: Towards an Architecture of Chromosome Maintenance Motif Patterns on Bacterial Genomes
Advisor: Torsten Waldminghaus


Internships and stays abroad
Sep. – Dec. 2015: Student Assistant at the Waldminghaus Lab, LOEWE Center for Synthetic Microbiology, Marburg (Germany). Focus: Programming and Data Analysis
Jan. – Apr. 2015: Internship at the Murray Lab, Center for Bacterial Cell Biology, Newcastle upon Tyne (United Kingdom). Focus: Bacterial Cell Cycle Regulation




Publications (ORCID)

  • D. Schindler, S. Milbredt, T. Sperlea, T. Waldminghaus: Design and Assembly of DNA Sequence Libraries for Chromosomal Insertion in Bacteria Based on a Set of Modified MoClo Vectors. ACS Synth Bio (2016) DOI: 10.1021/acssynbio.6b00089
  • N. Schallopp, S. Milbredt, T. Sperlea, M. Bruhn, F. Kemter, D. Schindler, T. Waldminghaus: Establishing a System for Testing Replication Inhibition of the Vibrio cholerae Secondary Chromosome in Escherichia coli. Antibiotics (2018) DOI: 10.3390/antibiotics7010003


Attended Conferences

December 2017: International Conference on Bioinformatics and Computational Biology (BBCC), Naples.
March 2017: Annual Conference of the Association for General and Applied Microbiology (VAAM), Würzburg; poster presentation.
September 2016: Annual Meeting of the German Genetics Society (GfG), Braunschweig; poster presentation.
March 2016: Annual Conference of the Association for General and Applied Microbiology (VAAM), Jena; poster presentation.
July 2015: CAS II – Synthetic Biology, Munich; poster presentation.
March 2015: 10th CeBiTec Symposium „Bioinformatics for Biotechnology and Biomedicine“, Bielefeld; poster presentation.